About PKD

What is polycystic kidney disease?

Polycystic kidney disease (PKD) is a genetic disease that often affects entire families for generations. PKD is one of the most common, life-threatening genetic diseases, and those affected by it are in urgent need of treatments and a cure. Here’s why:

  • Parents have a 50 percent chance of passing PKD to each of their children.
  • More than 50 percent of those affected by PKD will need dialysis or a kidney transplant by age 50.
  • PKD is the leading cause of kidney failure.
  • Dialysis and a kidney transplant are the only treatment options for those who have kidney failure.
  • A relatively rare form of PKD, autosomal recessive polycystic kidney disease (ARPKD), affects one in 20,000 children. ARPKD often causes death in the first month of life.
  • Approximately one-third of newborns who have ARPKD and survive their first month of life will need dialysis or a transplant by age 10.

Why support us

Our goal is to discover treatments that will improve the lives of those living with PKD, and one day find a cure to end PKD for good. To do this, we unite with energetic and compassionate volunteers and supporters across the country to fight PKD.

Need more reasons?

  • We are the largest private funder of PKD research.
  • We have been leading the fight against PKD for more than 30 years.
  • One hundred percent of your Walk donations go to PKD research to help bring treatments to patients faster.

Learn more about the PKD Foundation.